Carnosine

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Carnosine is a naturally-occurring dipeptide (a combination of two amino acids) found in muscles, brain and other human tissues.

Carnosine is a potent antioxidant and buffering agent.

VRP’s Carnosine is hydrazine free.

Supplement Facts
90 Capsules
Serving Size: 1 Capsule
Amount Per Serving
Carnosine 500 mg *

* Daily Value not established
Other Ingredients:
Microcrystalline cellulose and hydroxypropylmethylcellulose (Vcap).

Contains no added sugar, starch, salt, wheat, gluten,
corn, coloring, dairy products, flavoring or preservatives.

Keep container tightly closed in a cool,
dry and dark place. Keep out of reach of children.

Recommended Dosage: one to two capsules per day in divided doses on an empty stomach.

Carnosine contains the amino acids alanine and histidine, and is found in highest concentrations in long-lived tissues such as skeletal muscle, cardiac muscle and brain (Jackson and Lenney 1996), and has antioxidant, buffering, free radical scavenging and even neurotransmitter properties.

Visible Anti-aging Benefits
In a recent article in International Anti-Aging Systems Anti-Aging Bulletin, Dr Marios Kyriazis reported that his patients who take carnosine supplements often receive comments that they simply look younger. This may be a reflection of the phenomenon observed in in vitro experiments which show that carnosine actually rejuvenates older cells in culture (McFarland and Holliday, 1994), and in vivo animal experiments in which carnosine prevented the development of visible features of aging (Boldyrev, et. al., 1999). In that study, carnosine significantly delayed the appearance of skin ulcers, periopthalmic lesions, spinal lordokyphosis and behavioral responses such as activity and passive avoidance (all characteristic of aged animals). In another recent article, Russian scientists reported that not only did the carnosine-fed SAMP1 mice appear much more youthful than controls, but experienced a 20% increase in lifespan (Fig. 4) (Yuneva, et al, 1999).

Conclusion
Carnosine is generally considered an extremely non-toxic and safe substance. Boldyrev and other authors have reported that absorption of carnosine is excellent, perhaps greater than 70%. As with other antioxidants, carnosine acts synergistically when taken with other antioxidants. (For example, when vitamin E was taken with carnosine, levels of both substances were higher in cardiac muscle than when either was taken alone.)

Dr. Kyzarias, recommends 50–100 mg/day to his patients. He reports that noticeable benefits have been reported at this intake level. He also indicated that these levels were felt to be adequate by Alan Hipkiss, a top British and world researcher on carnosine at the University of London.

Additional information above courtesy and copyright Vitamin Research Products (VRP)

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