Huperzine A

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Huperzine A
60 capsules
Huperzine is a standardized extract from the Chinese club moss is an all-natural herbal supplement that may help prevent the breakdown of acetylcholine.*

Alzheimer's disease is a neurodegenerative disorder associated with neuritic plaques that affect the cerebral cortex, amygdala and hippocampus. There is also neurotransmission damage in the brain. One of the major functional deficits in Alzheimer's disease is a hypofunction of cholinergic neurons. This leads to the cholinergic hypothesis of Alzheimer's disease and the rationale for strategies to increase acetylcholine in the brains of Alzheimer's disease patients. Two FDA-approved drugs for the treatment of Alzheimer's disease, tacrine and donepezil, are acetylcholinesterase inhibitors.

In one double-blind, randomized study, huperzine A, in injectable form, was tested against a saline control in 56 patients with multi-infarct dementia or senile dementia and in 104 patients with senile and pre-senile simple memory disorders. Huperzine A produced significant positive effects as measured by the Wechsler Memory Scale. Dizziness was experienced by a few of the huperzine A-treated patients.

In another study, this one multicenter, double-blind, placebo-controlled and randomized, 50 subjects with Alzheimer's disease were given huperzine A or placebo for eight weeks. Significant improvement was noted in 58 percent of the patients in terms of memory, cognitive and behavioral functions. Research is ongoing.

This product is standardized for maximum efficacy, and its patented delivery system that includes fat-soluble vitamin E increases absorption.*

Supplement Facts
Serving Size 1 Capsule
Servings Per Container 60
Amount Per Serving
Vitamin E (as D-alpha tocopheryl acetate) 100 IU
Huperzine A (Huperzia serrata) (aerial plant) 50 mcg

Other ingredients: rice flour, gelatin, dicalcium phosphate.

Dosage and Use
Take one capsule daily, or as recommended by a healthcare practitioner.

Do not take more than four doses in any week, and do not use Huperzine A on a chronic basis.*

Caution
Because vitamin E inhibits blood clotting, it should not be used if excessive bleeding is occurring. Since Huperzine A inhibits the enzyme acetylcholinesterase, it should not be used on a chronic basis. The reason for this is that some acetylcholinesterase is needed to suppress excessive amounts of the neurotransmitter acetylcholine from accumulating in the body. While most people over age 30 need more acetylcholine, too much can cause unpleasant side effects. Most healthy people safety boost acetylcholine levels by taking precursors such as choline and phosphatidylcholine along with pantothenic acid. The COGNITEX formula contains these acetylcholine precursor agents. Do not take Huperzine A if you are taking other acetylcholinesterase inhibitors like Aricept or Tacrine.

INTERACTIONS
DRUGS
Acetylcholinesterase Inhibitors: Use of huperzine A along with the acetylcholinesterase inhibitors donepezil or tacrine may produce additive effects, including additive adverse effects. Other acetylcholinesterase inhibitors include neostigmine, physostigmine and pyridostigmine, and use of these agents along with huperzine A may produce additive effects, including additive adverse effects.
Cholinergic Drugs: Use of huperzine A along with cholinergic drugs, such as bethanechol, may produce additive effects, including additive adverse effects.

Because of possible adverse effects in those with seizure disorders, cardiac arrhythmias and asthma, those with these disorders should avoid huperzine A. Those with irritable bowel disease, inflammatory bowel disease and malabsorption syndromes should avoid huperzine A.

Warnings:
Keep out of reach of children.
Do not exceed recommended dose.
Do not purchase if outer seal is broken or damaged.
If you have a bad reaction to product discontinue use immediately.
When using nutritional supplements, please inform your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Purchase Huperzine A